Publications

Development and Preclinical Evaluation of an Integrase Defective Lentiviral Vector Vaccine Expressing the HIVACAT T Cell Immunogen in Mice.

Gallinaro A., Borghi M., Pirillo MF., Cecchetti S., Bona R., Canitano A., Michelini Z., Di Virgilio A., Olvera A., Brander C., Negri D., Cara A. Mol Ther Methods Clin Dev. 2020 Feb 4;17:418-428. doi: 10.1016/j.omtm.2020.01.013. eCollection 2020 Jun 12. PMID: 32154327.

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Recombinant BCG Expressing HTI Prime and Recombinant ChAdOx1 Boost Is Safe and Elicits HIV-1-Specific T-Cell Responses in BALB/c Mice.

Kilpeläinen A., Saubi N., Guitart N., Olvera A., Hanke T., Brander C., Joseph J. Vaccines (Basel). 2019 Aug 2;7(3). pii: E78. doi: 10.3390/vaccines7030078. PMID: 31382453.

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Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses.

Hancock G., Yang H., Yorke E., Wainwright E., Bourne V., Frisbee A., Payne TL., Berrong M., Ferrari G., Chopera D., Hanke T., Mothe B., Brander C., McElrath MJ., McMichael A., Goonetilleke N., Tomaras GD., Frahm N., Dorrell L. PLoS Pathog. 2015 Feb 27;11(2):e1004658. doi: 10.1371/journal.ppat.1004658. eCollection 2015 Feb. DOI: 10.1371/journal.ppat.1004658.

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Definition of the viral targets of protective HIV-1-specific T cell responses.

Mothe B., Llano A., Ibarrondo J., Daniels M., Miranda C., Zamarreño J., Bach V., Zuniga R., Pérez-Álvarez S., Berger CT., Puertas MC., Martinez-Picado J., Rolland M., Farfan M., Szinger JJ., Hildebrand WH., Yang OO., Sanchez-Merino V., Brumme CJ., Brumme ZL., Heckerman D., Allen TM., Mullins JI., Gómez G., Goulder PJ., Walker BD., Gatell JM., Clotet B., Korber BT., Sanchez J., Brander C. J Transl Med. 2011 Dec 7;9:208. doi: 10.1186/1479-5876-9-208. PMID: 22152067.

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A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques.

Mothe B., Hu X., Llano A., Rosati M., Olvera A., Kulkarni V., Valentin A., Alicea C., Pilkington GR., Sardesai NY., Rocafort M., Crespo M., Carrillo J., Marco A., Mullins JI., Dorrell L., Hanke T., Clotet B., Pavlakis GN., Felber BK., Brander C. J Transl Med. 2015 Feb 15;13:60. doi: 10.1186/s12967-015-0392-5. PMID: 25879820.

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